Dr Jawaher thiab abdelfattah Albderat

Biographic Data:

• 0777413889
• Pediatric nephrology consultant at private sector
• [email protected]
• Pediatric nephrology fellowship UK
• Fellow of the American and European Societies of Pediatric Nephrology.

Talk about Title:

Overview of Pediatric Kidney Disease: Epidemiology, Etiology, and Clinical Implications
Abstract:
Pediatric kidney disease encompasses a broad range of congenital and acquired disorders that affect renal development and function. Congenital anomalies of the kidney and urinary tract (CAKUT) represent the leading cause of chronic kidney disease (CKD) in children, accounting for nearly 50% of pediatric CKD cases [1]. Other significant etiologies include hereditary nephropathies such as Alport syndrome, and glomerular diseases including idiopathic nephrotic syndrome and post-infectious glomerulonephritis [2,3].
Acute kidney injury (AKI) is also a major concern, particularly in critically ill children, and is associated with increased morbidity, mortality, and risk of progression to CKD [4]. Early recognition and appropriate intervention are essential, as pediatric kidney disease can have long-term consequences on growth, neurodevelopment, and cardiovascular health [5].
Advancements in pediatric nephrology, including molecular diagnostics, renal imaging, and interdisciplinary care models, have improved diagnostic precision and patient outcomes [6]. However, disparities persist in access to care and early detection, particularly in low- and middle-income countries.
Efforts should focus on increasing awareness, promoting early screening in at-risk populations, and strengthening specialized pediatric nephrology services to improve outcomes and quality of life.

References:

1. Harambat J, van Stralen KJ, Kim JJ, Tizard EJ. Epidemiology of chronic kidney disease in children. Pediatr Nephrol. 2012;27(3):363–373. doi:10.1007/s00467-011-1939-1
2. Vivante A, Hildebrandt F. Exploring the genetic basis of early-onset chronic kidney disease. Nat Rev Nephrol. 2016;12(3):133–146. doi:10.1038/nrneph.2015.205
3. Gipson DS, Massengill SF, Yao L, et al. Management of childhood onset nephrotic syndrome. Pediatrics. 2009;124(2):747–757. doi:10.1542/peds.2008-1912
4. Selewski DT, Goldstein SL. Acute kidney injury in children: definitions, epidemiology, etiology, and outcomes. Curr Opin Pediatr. 2011;23(2):194–200. doi:10.1097/MOP.0b013e328343f4e4
5. Greenbaum LA, Warady BA, Furth SL. Current advances in chronic kidney disease in children: growth, cardiovascular complications, and outcomes. Curr Opin Pediatr. 2009;21(2):177–182. doi:10.1097/MOP.0b013e3283291db7
6. Haffner D, Schaefer F, Nissel R, et al. Effect of growth hormone treatment on adult height in chronic renal failure. N Engl J Med. 2000;343(13):923–930. doi:10.1056/NEJM200009283431302