{"id":2994,"date":"2025-04-21T08:03:49","date_gmt":"2025-04-21T08:03:49","guid":{"rendered":"https:\/\/portal.almaqasidhospital.com\/?p=2994"},"modified":"2025-04-21T08:03:49","modified_gmt":"2025-04-21T08:03:49","slug":"%d8%a7%d9%84%d8%af%d9%83%d8%aa%d9%88%d8%b1-%d8%a8%d8%a7%d8%b3%d9%85-%d8%a7%d9%84%d8%b2%d8%b9%d8%a8%d9%8a","status":"publish","type":"post","link":"https:\/\/portal.almaqasidhospital.com\/?p=2994","title":{"rendered":"\u0627\u0644\u062f\u0643\u062a\u0648\u0631 \u0628\u0627\u0633\u0645 \u0627\u0644\u0632\u0639\u0628\u064a"},"content":{"rendered":"<p dir=\"ltr\" style=\"text-align: left;\">\n<strong>DR.Bassem Mahmoud Hussein Al-Zoubi<\/strong><br \/>\nAbstract: Management of Short Stature<br \/>\nAbstract :<br \/>\nShort stature is a frequent pediatric presentation that can signal a range of underlying physiological or pathological conditions. It is defined as a height more than two standard deviations below the mean for age and sex (i.e., below the 2.3rd percentile on standardized growth charts) [1].<br \/>\nA structured and systematic approach to evaluation is essential to distinguish between normal variants of growth\u2014such as familial short stature and constitutional growth delay\u2014and pathological causes, including endocrine disorders (e.g., growth hormone deficiency, hypothyroidism), chronic systemic illnesses (e.g., gastrointestinal, renal, or cardiac disease), genetic syndromes (e.g., Turner syndrome, Noonan syndrome), and nutritional deficiencies [2].<br \/>\nInitial evaluation begins with a detailed growth history, review of perinatal factors, family height data, and growth velocity over time. Accurate anthropometric measurements, plotted on WHO or CDC growth charts, are vital. Bone age assessment via left hand-wrist radiography provides insight into growth potential and pubertal development [3].<br \/>\nFurther laboratory investigations should be guided by clinical suspicion and may include :<br \/>\n\u2022 Complete blood count and ESR to screen for chronic illness<br \/>\n\u2022 Thyroid function tests (TSH, free T4)<br \/>\n\u2022 Serum IGF-1 and IGFBP-3 as screening tools for growth hormone axis<br \/>\n\u2022 Karyotype (especially in girls with unexplained short stature to exclude Turner syndrome)<br \/>\n\u2022 Coeliac disease screening (tissue transglutaminase antibodies)<br \/>\n\u2022 Renal and liver function tests<br \/>\nIn cases with suspected growth hormone deficiency, a growth hormone stimulation test remains the gold standard for diagnosis [4].<br \/>\nManagement depends on the etiology:<br \/>\n\u2022 Nutritional and chronic disease-related short stature is addressed by treating the underlying condition.<br \/>\n\u2022 Endocrine disorders may require hormonal replacement therapy, such as levothyroxine for hypothyroidism or recombinant human growth hormone (rhGH) for GHD, Turner syndrome, chronic renal insufficiency, and other FDA-approved indications [5].<br \/>\n\u2022 Psychosocial support is essential to address the emotional impact of short stature and improve quality of life.<br \/>\nEarly detection and timely intervention are critical to optimizing final adult height and psychosocial outcomes. Close follow-up by pediatric endocrinologists is recommended for all children with pathological short stature.<br \/>\nKey References:<br \/>\n1. Rogol AD, Hayden GF. \u201cEtiologies and early diagnosis of short stature and growth failure in children and adolescents.\u201d J Pediatr. 2014;164(5 Suppl):S1\u2013S14. doi:10.1016\/j.jpeds.2014.02.027<br \/>\n2. Allen DB, Cuttler L. \u201cShort stature in childhood\u2014Challenges and choices.\u201d N Engl J Med. 2013;368(13):1220-1228. doi:10.1056\/NEJMcp1210380<br \/>\n3. Kaplowitz P, et al. \u201cEvaluation and referral of children with signs of early puberty or short stature: A pediatrician\u2019s guide.\u201d Pediatr Rev. 2016;37(7):259\u2013271.<br \/>\n4. Grimberg A, et al. \u201cGuidelines for growth hormone and insulin-like growth factor-I treatment in children and adolescents: Growth hormone deficiency, idiopathic short stature, and primary insulin-like growth factor-I deficiency.\u201d Horm Res Paediatr. 2016;86(6):361\u2013397.<br \/>\n5. Cohen P, et al. \u201cConsensus statement on the diagnosis and treatment of children with idiopathic short stature: A summary of the Growth Hormone Research Society, the Lawson Wilkins Pediatric Endocrine Society, and the European Society for Paediatric Endocrinology.\u201d J Clin Endocrinol Metab. 2008;93(11):4210\u20134217.<\/p>\n<p dir=\"ltr\" style=\"text-align: left;\">\n","protected":false},"excerpt":{"rendered":"<p>DR.Bassem Mahmoud Hussein Al-Zoubi Abstract: Management of Short Stature Abstract : Short stature is a frequent pediatric presentation that can signal a range of underlying physiological or pathological conditions. It is defined as a height more than two standard deviations below the mean for age and sex (i.e., below the 2.3rd percentile on standardized growth [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[82],"tags":[],"class_list":["post-2994","post","type-post","status-publish","format-standard","hentry","category-82"],"acf":[],"_links":{"self":[{"href":"https:\/\/portal.almaqasidhospital.com\/index.php?rest_route=\/wp\/v2\/posts\/2994","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/portal.almaqasidhospital.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/portal.almaqasidhospital.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/portal.almaqasidhospital.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/portal.almaqasidhospital.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2994"}],"version-history":[{"count":2,"href":"https:\/\/portal.almaqasidhospital.com\/index.php?rest_route=\/wp\/v2\/posts\/2994\/revisions"}],"predecessor-version":[{"id":2996,"href":"https:\/\/portal.almaqasidhospital.com\/index.php?rest_route=\/wp\/v2\/posts\/2994\/revisions\/2996"}],"wp:attachment":[{"href":"https:\/\/portal.almaqasidhospital.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2994"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/portal.almaqasidhospital.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2994"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/portal.almaqasidhospital.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2994"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}